Dectin-2-Dependent NKT Cell Activation and Serotype-Specific Antibody Production in Mice Immunized with Pneumococcal Polysaccharide Vaccine

Although thymus-independent type 2 antigens generally do not undergo Ig class switching from IgM to IgG, pneumococcal polysaccharide vaccine (PPV) induces the production of serotype-specific IgG. How this happens remains unclear, however. In the present study, PPV immunization induced production of...

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Detalhes bibliográficos
Main Authors: Miyasaka, Tomomitsu, Akahori, Yukiko, Toyama, Masahiko, Miyamura, Namiko, Ishii, Keiko, Saijo, Shinobu, Iwakura, Yoichiro, Kinjo, Yuki, Miyazaki, Yoshitsugu, Oishi, Kazunori, Kawakami, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808275/
https://ncbi.nlm.nih.gov/pubmed/24205278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078611
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