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Dectin-2 Regulates the Effector Phase of House Dust Mite-Elicited Pulmonary Inflammation Independently from its Role in Sensitization

The myeloid C-type lectin receptor Dectin-2 directs the generation of Th2 and Th17 immune responses to the house dust mite Dermatophagoides farinae (Df) through the generation of cysteinyl leukotrienes (cys-LTs) and pro-inflammatory cytokines, respectively, but a role for Dectin-2 in effector phase...

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Autores principales: Parsons, Matthew W., Li, Li, Wallace, Aaron M., Lee, Min Jung, Katz, Howard R., Fernandez, James M., Saijo, Shinobu, Iwakura, Yoichiro, Austen, K. Frank, Kanaoka, Yoshihide, Barrett, Nora A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024442/
https://ncbi.nlm.nih.gov/pubmed/24453247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301809
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