Antiproliferation of berberine is mediated by epigenetic modification of constitutive androstane receptor (CAR) metabolic pathway in hepatoma cells

Constitutive androstane receptor (CAR) regulates hepatic xenobiotic and energy metabolism, as well as promotes cell growth and hepatocarcinogenesis. Berberine is an ancient multipotent alkaloid drug which derived from Coptis chinensis plants. Here we report that berberine is able to be cellular upta...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhang, Lei, Miao, Xiao-Jie, Wang, Xin, Pan, Hai-Hui, Li, Pu, Ren, Hong, Jia, Yong-Rui, Lu, Chuang, Wang, Hong-Bing, Yuan, Lan, Zhang, Guo-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911599/
https://ncbi.nlm.nih.gov/pubmed/27311637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28116
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi