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TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

When integral membrane proteins are visualized in detergents or other artificial systems, an important layer of information is lost regarding lipid interactions and their effects on protein structure. This is especially relevant to proteins for which lipids play both structural and regulatory roles....

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Gao, Yuan, Cao, Erhu, Julius, David, Cheng, Yifan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911334/
https://ncbi.nlm.nih.gov/pubmed/27281200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17964
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