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TRPV1 structures in distinct conformations reveal mechanisms of activation

TRP channels are polymodal signal detectors that respond to a wide range of physical and chemical stimuli. Elucidating how these channels integrate and convert physiological signals into channel opening is essential to understanding how they regulate cell excitability under normal and pathophysiolog...

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Bibliografske podrobnosti
Main Authors: Cao, Erhu, Liao, Maofu, Cheng, Yifan, Julius, David
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023639/
https://ncbi.nlm.nih.gov/pubmed/24305161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12823
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