Caricamento...
Phosphorylation of Ca(v)1.2 on S1928 uncouples the L‐type Ca(2+) channel from the β(2) adrenergic receptor
Agonist‐triggered downregulation of β‐adrenergic receptors (ARs) constitutes vital negative feedback to prevent cellular overexcitation. Here, we report a novel downregulation of β(2) AR signaling highly specific for Ca(v)1.2. We find that β(2)‐AR binding to Ca(v)1.2 residues 1923–1942 is required f...
Salvato in:
| Pubblicato in: | EMBO J |
|---|---|
| Autori principali: | , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910527/ https://ncbi.nlm.nih.gov/pubmed/27103070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593409 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|