Phosphorylation of Ser(1928) mediates the enhanced activity of the L-type Ca(2+) channel Ca(v)1.2 by the β(2)-adrenergic receptor in neurons

The L-type Ca(2+) channel Ca(v)1.2 controls multiple functions throughout the body including heart rate and neuronal excitability. It is a key mediator of fight-or-flight stress responses triggered by a signaling pathway involving β-adrenergic receptors (βARs), cyclic adenosine monophosphate (cAMP),...

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Publicado no:Sci Signal
Main Authors: Qian, Hai, Patriarchi, Tommaso, Price, Jennifer L., Matt, Lucas, Lee, Boram, Nieves-Cintrón, Madeline, Buonarati, Olivia R., Chowdhury, Dhrubajyoti, Nanou, Evanthia, Nystoriak, Matthew A., Catterall, William A., Poomvanicha, Montatip, Hofmann, Franz, Navedo, Manuel F., Hell, Johannes W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310946/
https://ncbi.nlm.nih.gov/pubmed/28119465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf9659
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