The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis

High level of collagen deposition in human and mouse breast tumors are associated with poor outcome due to increased local invasion and distant metastases. Using a genetic approach we show, in mice, that the action of the fibrillar collagen receptor, discoidin domain receptor 2 (DDR2) in both tumor...

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Vydáno v:Cell Rep
Hlavní autoři: Corsa, Callie A. S., Brenot, Audrey, Grither, Whitney R., Van Hove, Samantha, Loza, Andrew J., Zhang, Kun, Ponik, Suzanne M., Liu, Yuming, DeNardo, David G., Eliceiri, Kevin W., Keely, Patricia J., Longmore, Gregory D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909540/
https://ncbi.nlm.nih.gov/pubmed/27264173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.033
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