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SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion

The EMT inducer SNAIL1 regulates breast cancer metastasis and its expression in human primary breast tumor predicts for poor outcomes. During tumor progression SNAIL1 has multiple effects in tumor cells that can impact metastasis. An inflammatory tumor microenvironment also impacts metastasis and re...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Brenot, Audrey, Knolhoff, Brett L., DeNardo, David G., Longmore, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874242/
https://ncbi.nlm.nih.gov/pubmed/29593211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0042-x
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