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The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis
High level of collagen deposition in human and mouse breast tumors are associated with poor outcome due to increased local invasion and distant metastases. Using a genetic approach we show, in mice, that the action of the fibrillar collagen receptor, discoidin domain receptor 2 (DDR2) in both tumor...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909540/ https://ncbi.nlm.nih.gov/pubmed/27264173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.033 |
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