The action of Discoidin Domain Receptor 2 in basal tumor cells and stromal Cancer Associated Fibroblasts is critical for breast cancer metastasis

High level of collagen deposition in human and mouse breast tumors are associated with poor outcome due to increased local invasion and distant metastases. Using a genetic approach we show, in mice, that the action of the fibrillar collagen receptor, discoidin domain receptor 2 (DDR2) in both tumor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Corsa, Callie A. S., Brenot, Audrey, Grither, Whitney R., Van Hove, Samantha, Loza, Andrew J., Zhang, Kun, Ponik, Suzanne M., Liu, Yuming, DeNardo, David G., Eliceiri, Kevin W., Keely, Patricia J., Longmore, Gregory D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909540/
https://ncbi.nlm.nih.gov/pubmed/27264173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.033
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge