Nalaganje...
Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function
Thrombin is a highly plastic molecule whose activity and specificity are regulated by exosites 1 and 2, positively-charged domains that flank the active site. Exosite binding by substrates and cofactors regulates thrombin activity by localizing thrombin, guiding substrates, and by inducing allosteri...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909201/ https://ncbi.nlm.nih.gov/pubmed/27305147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157471 |
| Oznake: |
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