Chargement en cours...
Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function
Thrombin is a highly plastic molecule whose activity and specificity are regulated by exosites 1 and 2, positively-charged domains that flank the active site. Exosite binding by substrates and cofactors regulates thrombin activity by localizing thrombin, guiding substrates, and by inducing allosteri...
Enregistré dans:
| Publié dans: | PLoS One |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909201/ https://ncbi.nlm.nih.gov/pubmed/27305147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157471 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|