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Polymorphic Mutation Frequencies in Escherichia coli: Emergence of Weak Mutators in Clinical Isolates

Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 × 10(−8) ≤ f < 4 × 10(−7)), and 0.7% were strongly hypermutable (f ≥ 4 × 10(−7)). Weak mutators were ap...

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Main Authors: Baquero, María-Rosario, Nilsson, Annika I., del Carmen Turrientes, María, Sandvang, Dorthe, Galán, Juan Carlos, Martínez, Jose Luís, Frimodt-Møller, Niels, Baquero, Fernando, Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC490890/
https://ncbi.nlm.nih.gov/pubmed/15292159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.16.5538-5542.2004
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