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Biological Cost of Single and Multiple Norfloxacin Resistance Mutations in Escherichia coli Implicated in Urinary Tract Infections

Resistance to fluoroquinolones in urinary tract infection (UTIs) caused by Escherichia coli is associated with multiple mutations, typically those that alter DNA gyrase and DNA topoisomerase IV and those that regulate AcrAB-TolC-mediated efflux. We asked whether a fitness cost is associated with the...

詳細記述

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書誌詳細
主要な著者: Lindgren, Patricia Komp, Marcusson, Linda L., Sandvang, Dorthe, Frimodt-Møller, Niels, Hughes, Diarmaid
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140522/
https://ncbi.nlm.nih.gov/pubmed/15917531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2343-2351.2005
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