Polymorphic Mutation Frequencies in Escherichia coli: Emergence of Weak Mutators in Clinical Isolates

Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 × 10(−8) ≤ f < 4 × 10(−7)), and 0.7% were strongly hypermutable (f ≥ 4 × 10(−7)). Weak mutators were ap...

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Главные авторы: Baquero, María-Rosario, Nilsson, Annika I., del Carmen Turrientes, María, Sandvang, Dorthe, Galán, Juan Carlos, Martínez, Jose Luís, Frimodt-Møller, Niels, Baquero, Fernando, Andersson, Dan I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2004
Предметы:
Population Genetics and Evolution
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC490890/
https://ncbi.nlm.nih.gov/pubmed/15292159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.16.5538-5542.2004
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