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Frequency of Mutation to Rifampin Resistance in Streptococcus pneumoniae Clinical Strains: hexA and hexB Polymorphisms Do Not Account for Hypermutation
The frequency of mutation to rifampin resistance of 200 clinical Streptococcus pneumoniae isolates was examined. Two peaks were observed in the distribution, with mode frequencies of 2.5 × 10(−7) (20% of isolates) and 2.5 × 10(−8). The hexA and hexB gene entire sequences were analyzed in 13 isolates...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152530/ https://ncbi.nlm.nih.gov/pubmed/12654695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1464-1467.2003 |
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