Frequency of Mutation to Rifampin Resistance in Streptococcus pneumoniae Clinical Strains: hexA and hexB Polymorphisms Do Not Account for Hypermutation

The frequency of mutation to rifampin resistance of 200 clinical Streptococcus pneumoniae isolates was examined. Two peaks were observed in the distribution, with mode frequencies of 2.5 × 10(−7) (20% of isolates) and 2.5 × 10(−8). The hexA and hexB gene entire sequences were analyzed in 13 isolates...

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Bibliografski detalji
Glavni autori: Morosini, María-Isabel, Baquero, María-Rosario, Sánchez-Romero, J. M., Negri, María-Cristina, Galán, Juan-Carlos, del Campo, Rosa, Pérez-Díaz, J. C., Baquero, Fernando
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Mechanisms of Resistance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC152530/
https://ncbi.nlm.nih.gov/pubmed/12654695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1464-1467.2003
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