Polymorphic Mutation Frequencies in Escherichia coli: Emergence of Weak Mutators in Clinical Isolates

Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 × 10(−8) ≤ f < 4 × 10(−7)), and 0.7% were strongly hypermutable (f ≥ 4 × 10(−7)). Weak mutators were ap...

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Detalhes bibliográficos
Main Authors: Baquero, María-Rosario, Nilsson, Annika I., del Carmen Turrientes, María, Sandvang, Dorthe, Galán, Juan Carlos, Martínez, Jose Luís, Frimodt-Møller, Niels, Baquero, Fernando, Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Population Genetics and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC490890/
https://ncbi.nlm.nih.gov/pubmed/15292159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.16.5538-5542.2004
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