Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Antibody 10E8 targets the membrane-proximal external region (MPER) of HIV-1 gp41, neutralizes >97% of HIV-1 isolates, and lacks the auto-reactivity often associated with MPER-directed antibodies. The developmental pathway of 10E8 might therefore serve as a promising template for vaccine design, b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Soto, Cinque, Ofek, Gilad, Joyce, M. Gordon, Zhang, Baoshan, McKee, Krisha, Longo, Nancy S., Yang, Yongping, Huang, Jinghe, Parks, Robert, Eudailey, Joshua, Lloyd, Krissey E., Alam, S. Munir, Haynes, Barton F., Mullikin, James C., Connors, Mark, Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907498/
https://ncbi.nlm.nih.gov/pubmed/27299673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157409
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