Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Antibody 10E8 targets the membrane-proximal external region (MPER) of HIV-1 gp41, neutralizes >97% of HIV-1 isolates, and lacks the auto-reactivity often associated with MPER-directed antibodies. The developmental pathway of 10E8 might therefore serve as a promising template for vaccine design, b...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Soto, Cinque, Ofek, Gilad, Joyce, M. Gordon, Zhang, Baoshan, McKee, Krisha, Longo, Nancy S., Yang, Yongping, Huang, Jinghe, Parks, Robert, Eudailey, Joshua, Lloyd, Krissey E., Alam, S. Munir, Haynes, Barton F., Mullikin, James C., Connors, Mark, Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907498/
https://ncbi.nlm.nih.gov/pubmed/27299673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157409
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