Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection

Background. The elderly host is highly susceptible to severe disease and treatment failure in Clostridium difficile infection (CDI). We investigated how treatment with vancomycin in the aged host influences systemic and intestinal humoral responses and select intestinal microbiota. Methods. Young (a...

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Publicado en:J Infect Dis
Autores principales: van Opstal, Edward, Kolling, Glynis L., Moore, John H., Coquery, Christine M., Wade, Nekeithia S., Loo, William M., Bolick, David T., Shin, Jae Hyun, Erickson, Loren D., Warren, Cirle A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907406/
https://ncbi.nlm.nih.gov/pubmed/26917573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw071
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