Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection

Background. The elderly host is highly susceptible to severe disease and treatment failure in Clostridium difficile infection (CDI). We investigated how treatment with vancomycin in the aged host influences systemic and intestinal humoral responses and select intestinal microbiota. Methods. Young (a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Infect Dis
Prif Awduron: van Opstal, Edward, Kolling, Glynis L., Moore, John H., Coquery, Christine M., Wade, Nekeithia S., Loo, William M., Bolick, David T., Shin, Jae Hyun, Erickson, Loren D., Warren, Cirle A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Major Articles and Brief Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907406/
https://ncbi.nlm.nih.gov/pubmed/26917573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw071
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