Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection

Background. The elderly host is highly susceptible to severe disease and treatment failure in Clostridium difficile infection (CDI). We investigated how treatment with vancomycin in the aged host influences systemic and intestinal humoral responses and select intestinal microbiota. Methods. Young (a...

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Библиографические подробности
Опубликовано в: :J Infect Dis
Главные авторы: van Opstal, Edward, Kolling, Glynis L., Moore, John H., Coquery, Christine M., Wade, Nekeithia S., Loo, William M., Bolick, David T., Shin, Jae Hyun, Erickson, Loren D., Warren, Cirle A.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907406/
https://ncbi.nlm.nih.gov/pubmed/26917573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw071
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