Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection

Background. The elderly host is highly susceptible to severe disease and treatment failure in Clostridium difficile infection (CDI). We investigated how treatment with vancomycin in the aged host influences systemic and intestinal humoral responses and select intestinal microbiota. Methods. Young (a...

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Vydáno v:J Infect Dis
Hlavní autoři: van Opstal, Edward, Kolling, Glynis L., Moore, John H., Coquery, Christine M., Wade, Nekeithia S., Loo, William M., Bolick, David T., Shin, Jae Hyun, Erickson, Loren D., Warren, Cirle A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907406/
https://ncbi.nlm.nih.gov/pubmed/26917573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw071
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