Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection

Background. The elderly host is highly susceptible to severe disease and treatment failure in Clostridium difficile infection (CDI). We investigated how treatment with vancomycin in the aged host influences systemic and intestinal humoral responses and select intestinal microbiota. Methods. Young (a...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: van Opstal, Edward, Kolling, Glynis L., Moore, John H., Coquery, Christine M., Wade, Nekeithia S., Loo, William M., Bolick, David T., Shin, Jae Hyun, Erickson, Loren D., Warren, Cirle A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907406/
https://ncbi.nlm.nih.gov/pubmed/26917573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw071
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