Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions

AML1-ETO is the translational product of a chimeric gene created by the stable chromosome translocation t (8;21)(q22;q22). It causes acute myeloid leukemia (AML) by dysregulating the expression of genes critical for myeloid cell development and differentiation and recently has been reported to bind...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Roh, Soung-Hun, Kasembeli, Moses M., Galaz-Montoya, Jesús G., Chiu, Wah, Tweardy, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2016
Soggetti:
Proteins
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906440/
https://ncbi.nlm.nih.gov/pubmed/27276256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.04.045
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi