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Crystal structure of NOD2 and its implications in human disease

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), a member of the NOD-like receptors family, are crucial for innate immune responses. Mutations of NOD2 have been associated with chronic inflammatory disorders such as Crohn's disease (CD), Blau syndrome (BS) and early-onset...

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Vydáno v:Nat Commun
Hlavní autoři: Maekawa, Sakiko, Ohto, Umeharu, Shibata, Takuma, Miyake, Kensuke, Shimizu, Toshiyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906405/
https://ncbi.nlm.nih.gov/pubmed/27283905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11813
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