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Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis

ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is to identify the molecular mechanism(s) underlying ABCA1 epigenetic modification and determine its potential impact on ABCA1 expression in macrophage-derived...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Lv, Yun-Cheng, Tang, Yan-Yan, Zhang, Ping, Wan, Wei, Yao, Feng, He, Ping-Ping, Xie, Wei, Mo, Zhong-Cheng, Shi, Jin-Feng, Wu, Jian-Feng, Peng, Juan, Liu, Dan, Cayabyab, Francisco S., Zheng, Xi-Long, Tang, Xiang-Yang, Ouyang, Xin-Ping, Tang, Chao-Ke
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905646/
https://ncbi.nlm.nih.gov/pubmed/27295295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157265
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