Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis

ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is to identify the molecular mechanism(s) underlying ABCA1 epigenetic modification and determine its potential impact on ABCA1 expression in macrophage-derived...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lv, Yun-Cheng, Tang, Yan-Yan, Zhang, Ping, Wan, Wei, Yao, Feng, He, Ping-Ping, Xie, Wei, Mo, Zhong-Cheng, Shi, Jin-Feng, Wu, Jian-Feng, Peng, Juan, Liu, Dan, Cayabyab, Francisco S., Zheng, Xi-Long, Tang, Xiang-Yang, Ouyang, Xin-Ping, Tang, Chao-Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905646/
https://ncbi.nlm.nih.gov/pubmed/27295295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157265
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