Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis.

ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is to identify the molecular mechanism(s) underlying ABCA1 epigenetic modification and determine its potential impact on ABCA1 expression in macrophage-derived...

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Autori principali: Yun-Cheng Lv, Yan-Yan Tang, Ping Zhang, Wei Wan, Feng Yao, Ping-Ping He, Wei Xie, Zhong-Cheng Mo, Jin-Feng Shi, Jian-Feng Wu, Juan Peng, Dan Liu, Francisco S Cayabyab, Xi-Long Zheng, Xiang-Yang Tang, Xin-Ping Ouyang, Chao-Ke Tang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4905646?pdf=render
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