Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6), a novel pCAF and Gcn5 histone acet...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Di Martile, Marta, Desideri, Marianna, De Luca, Teresa, Gabellini, Chiara, Buglioni, Simonetta, Eramo, Adriana, Sette, Giovanni, Milella, Michele, Rotili, Dante, Mai, Antonello, Carradori, Simone, Secci, Daniela, De Maria, Ruggero, Del Bufalo, Donatella, Trisciuoglio, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905477/
https://ncbi.nlm.nih.gov/pubmed/26870991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7238
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker