Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6), a novel pCAF and Gcn5 histone acet...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Di Martile, Marta, Desideri, Marianna, De Luca, Teresa, Gabellini, Chiara, Buglioni, Simonetta, Eramo, Adriana, Sette, Giovanni, Milella, Michele, Rotili, Dante, Mai, Antonello, Carradori, Simone, Secci, Daniela, De Maria, Ruggero, Del Bufalo, Donatella, Trisciuoglio, Daniela
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905477/
https://ncbi.nlm.nih.gov/pubmed/26870991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7238
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