The thiazole derivative CPTH6 impairs autophagy

We have previously demonstrated that the thiazole derivative 3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6) induces apoptosis and cell cycle arrest in human leukemia cells. The aim of this study was to evaluate whether CPTH6 is able to affect autophagy. By using several...

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Hlavní autoři: Ragazzoni, Y, Desideri, M, Gabellini, C, De Luca, T, Carradori, S, Secci, D, Nescatelli, R, Candiloro, A, Condello, M, Meschini, S, Del Bufalo, D, Trisciuoglio, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613831/
https://ncbi.nlm.nih.gov/pubmed/23470531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.53
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