Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells

In addition to act as an antiapoptotic protein, B-cell lymphoma (bcl)-2 can also promote tumor angiogenesis. In this context, we have previously demonstrated that under hypoxia bcl-2 promotes hypoxia-inducible factor-1 (HIF-1)-mediated vascular endothelial growth factor (VEGF) expression in melanoma...

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Bibliografske podrobnosti
Main Authors: Trisciuoglio, D, Gabellini, C, Desideri, M, Ragazzoni, Y, De Luca, T, Ziparo, E, Del Bufalo, D
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131942/
https://ncbi.nlm.nih.gov/pubmed/21233846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.175
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