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Involvement of PI3K and MAPK Signaling in bcl-2-induced Vascular Endothelial Growth Factor Expression in Melanoma Cells

We have previously demonstrated that bcl-2 overexpression in tumor cells exposed to hypoxia increases the expression of vascular endothelial growth factor (VEGF) gene through the hypoxia-inducible factor-1 (HIF-1). In this article, we demonstrate that exposure of bcl-2 overexpressing melanoma cells...

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Detalles Bibliográficos
Main Authors: Trisciuoglio, Daniela, Iervolino, Angela, Zupi, Gabriella, Del Bufalo, Donatella
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196326/
https://ncbi.nlm.nih.gov/pubmed/15987743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1087
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