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Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells

The Wnt/β-catenin signaling pathway is critical for the initiation and progression of most colon cancers, and has emerged as one of the most promising targets for colorectal cancer chemoprevention and treatment. In this study, we have discovered a structurally related series of quinazolines as poten...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Li, Yonghe, Lu, Wenyan, Saini, Surendra K., Moukha-Chafiq, Omar, Pathak, Vibha, Ananthan, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905471/
https://ncbi.nlm.nih.gov/pubmed/26820295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7019
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