Studies of the Biogenic Amine Transporters 15. Identification of Novel Allosteric Dopamine Transporter Ligands with Nanomolar Potency

Novel allosteric modulators of the dopamine transporter (DAT) have been identified. We have shown previously that SRI-9804 [N-(diphenylmethyl)-2-phenyl-4-quinazolinamine], SRI-20040 [N-(2,2-diphenylethyl)-2-phenyl-4-quinazolinamine], and SRI-20041 [N-(3,3-diphenylpropyl)-2-phenyl-4-quinazolinamine]...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Rothman, Richard B., Ananthan, Subramaniam, Partilla, John S., Saini, Surendra K., Moukha-Chafiq, Omar, Pathak, Vibha, Baumann, Michael H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2015
Témata:
Neuropharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429677/
https://ncbi.nlm.nih.gov/pubmed/25788711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.222299
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