SRI36160 is a specific inhibitor of Wnt/β-catenin signaling in human pancreatic and colorectal cancer cells

Activation of Wnt/β-catenin signaling is associated with pancreatic and colorectal cancer, among others. To-date, there are no FDA-approved small molecule Wnt/β-catenin inhibitors and many past efforts resulted in compounds with undesirable off-target effects. We recently identified a series of benz...

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Vydáno v:Cancer Lett
Hlavní autoři: Li, Yonghe, Oliver, Patsy G., Lu, Wenyan, Pathak, Vibha, Sridharan, Sivaram, Augelli-Szafran, Corinne E., Buchsbaum, Donald J., Suto, Mark J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544029/
https://ncbi.nlm.nih.gov/pubmed/28043913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.12.030
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