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A cancerous web: signaling, metabolism, and the epigenome

Histone acetylation is sensitive to the availability of acetyl-CoA. However, the extent to which metabolic alterations in cancer cells impact tumor histone acetylation has been unclear. Here, we discuss our recent findings that oncogenic AKT1 activation regulates histone acetylation levels in tumors...

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Vydáno v:Mol Cell Oncol
Hlavní autoři: Lee, Joyce V., Shah, Supriya, Carrer, Alessandro, Wellen, Kathryn E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904988/
https://ncbi.nlm.nih.gov/pubmed/27308412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.965620
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