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The folate cycle is a new metabolic weakness of cancer
Cancer cells harness nutrients to support its rapid proliferation through metabolic reprogramming. Our report identified folate cycle as a metabolic target in hepatocellular carcinoma. Folate cycle stagnation via inhibition of its mitochondrial folate enzyme methylenetetrahydrofolate dehydrogenase 1...
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| Veröffentlicht in: | Mol Cell Oncol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706950/ https://ncbi.nlm.nih.gov/pubmed/29209641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1327004 |
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