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The folate cycle is a new metabolic weakness of cancer

Cancer cells harness nutrients to support its rapid proliferation through metabolic reprogramming. Our report identified folate cycle as a metabolic target in hepatocellular carcinoma. Folate cycle stagnation via inhibition of its mitochondrial folate enzyme methylenetetrahydrofolate dehydrogenase 1...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Lee, Derek, Wong, Carmen Chak-Lui
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706950/
https://ncbi.nlm.nih.gov/pubmed/29209641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1327004
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