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Activated Protein C Promotes Neuroprotection: Mechanisms and Translation to the Clinic

Activated protein C (APC) is a plasma serine protease that is capable of antithrombotic, anti-inflammatory, anti-apoptotic, and cell-signaling activities. Animal injury studies show that recombinant APC and some of its mutants are remarkably therapeutic for a wide range of injuries. In particular, f...

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Detalhes bibliográficos
Publicado no:Thromb Res
Main Authors: Griffin, John H., Fernández, José A., Lyden, Patrick D., Zlokovic, Berislav V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904825/
https://ncbi.nlm.nih.gov/pubmed/27207428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0049-3848(16)30368-1
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