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Activated Protein C Promotes Neovascularization and Neurogenesis in Postischemic Brain via Protease-Activated Receptor 1

Activated protein C (APC) is a serine protease with anticoagulant and direct cytoprotective activities. Early postischemic APC application activates the cellular protein C pathway in brain endothelium and neurons, which is neuroprotective. Whether late APC administration after a transient ischemic a...

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Bibliografiska uppgifter
Huvudupphovsmän: Thiyagarajan, Meenakshisundaram, Fernández, José A., Lane, Steven M., Griffin, John H., Zlokovic, Berislav V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742231/
https://ncbi.nlm.nih.gov/pubmed/19036971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3485-08.2008
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