GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain

[Image: see text] The BRPF (Bromodomain and PHD Finger-containing) protein family are important scaffolding proteins for assembly of MYST histone acetyltransferase complexes. A selective benzimidazolone BRPF1 inhibitor showing micromolar activity in a cellular target engagement assay was recently de...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Bamborough, Paul, Barnett, Heather A., Becher, Isabelle, Bird, Mark J., Chung, Chun-wa, Craggs, Peter D., Demont, Emmanuel H., Diallo, Hawa, Fallon, David J., Gordon, Laurie J., Grandi, Paola, Hobbs, Clare I., Hooper-Greenhill, Edward, Jones, Emma J., Law, Robert P., Le Gall, Armelle, Lugo, David, Michon, Anne-Marie, Mitchell, Darren J., Prinjha, Rab K., Sheppard, Robert J., Watson, Allan J. B., Watson, Robert J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904261/
https://ncbi.nlm.nih.gov/pubmed/27326325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00092
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller