GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain

[Image: see text] The BRPF (Bromodomain and PHD Finger-containing) protein family are important scaffolding proteins for assembly of MYST histone acetyltransferase complexes. A selective benzimidazolone BRPF1 inhibitor showing micromolar activity in a cellular target engagement assay was recently de...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Bamborough, Paul, Barnett, Heather A., Becher, Isabelle, Bird, Mark J., Chung, Chun-wa, Craggs, Peter D., Demont, Emmanuel H., Diallo, Hawa, Fallon, David J., Gordon, Laurie J., Grandi, Paola, Hobbs, Clare I., Hooper-Greenhill, Edward, Jones, Emma J., Law, Robert P., Le Gall, Armelle, Lugo, David, Michon, Anne-Marie, Mitchell, Darren J., Prinjha, Rab K., Sheppard, Robert J., Watson, Allan J. B., Watson, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904261/
https://ncbi.nlm.nih.gov/pubmed/27326325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00092
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados