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Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain

BRPF1 is part of the MOZ HAT complex and contains a unique combination of domains typically found in chromatin-associated factors, which include PHD fingers, a bromodomain and a PWWP domain. Bromodomains are conserved structural motifs generally known to recognize acetylated histones, and the BRPF1...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Lubula, Mulu Y., Eckenroth, Brian E., Carlson, Samuel, Poplawski, Amanda, Chruszcz, Maksymilian, Glass, Karen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252766/
https://ncbi.nlm.nih.gov/pubmed/25281266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.09.028
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