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Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain
The ATPase family, AAA domain-containing protein 2 (ATAD2) has a C-terminal bromodomain, which functions as a chromatin reader domain recognizing acetylated lysine on the histone tails within the nucleosome. ATAD2 is overexpressed in many cancers and its expression is correlated with poor patient ou...
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| Veröffentlicht in: | Proteins |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6457126/ https://ncbi.nlm.nih.gov/pubmed/30520161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25636 |
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