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The ATAD2 bromodomain binds different acetylation marks on the histone H4 in similar fuzzy complexes
Bromodomains are protein modules adopting conserved helix bundle folds. Some bromodomain-containing proteins, such as ATPase family AAA domain-containing protein 2 (ATAD2), isoform A, have attracted much interest because they are overexpressed in many types of cancer. Bromodomains bind to acetylated...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5633134/ https://ncbi.nlm.nih.gov/pubmed/28798233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786350 |
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