The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells

Gfi1 plays an important role in the development and maintenance of many hematopoietic linage cells. However, the impact of Gfi1-deficiency on the iNKT cell differentiation remains unclear. We herein demonstrate a critical role of Gfi1 in regulating the development of iNKT cell subsets. In the thymus...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yasuoka, Toshiaki, Kuwahara, Makoto, Yamada, Takeshi, Maruyama, Saho, Suzuki, Junpei, Taniguchi, Masaru, Yasukawa, Masaki, Yamashita, Masakatsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902269/
https://ncbi.nlm.nih.gov/pubmed/27284976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157395
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