Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells

A transcriptional repressor Gfi1 promotes T helper type 2 (Th2) cell development and inhibits Th17 and inducible regulatory T‐cell differentiation. However, the role of Gfi1 in regulating Th1 cell differentiation and the Th1‐type immune response remains to be investigated. We herein demonstrate that...

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Veröffentlicht in:Immunology
Hauptverfasser: Suzuki, Junpei, Maruyama, Saho, Tamauchi, Hidekazu, Kuwahara, Makoto, Horiuchi, Mika, Mizuki, Masumi, Ochi, Mizuki, Sawasaki, Tatsuya, Zhu, Jinfang, Yasukawa, Masaki, Yamashita, Masakatsu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799889/
https://ncbi.nlm.nih.gov/pubmed/26749286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12580
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