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Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells

A transcriptional repressor Gfi1 promotes T helper type 2 (Th2) cell development and inhibits Th17 and inducible regulatory T‐cell differentiation. However, the role of Gfi1 in regulating Th1 cell differentiation and the Th1‐type immune response remains to be investigated. We herein demonstrate that...

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Bibliographic Details
Published in:Immunology
Main Authors: Suzuki, Junpei, Maruyama, Saho, Tamauchi, Hidekazu, Kuwahara, Makoto, Horiuchi, Mika, Mizuki, Masumi, Ochi, Mizuki, Sawasaki, Tatsuya, Zhu, Jinfang, Yasukawa, Masaki, Yamashita, Masakatsu
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799889/
https://ncbi.nlm.nih.gov/pubmed/26749286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12580
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