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Targets of the transcriptional repressor oncoprotein Gfi-1

Gfi-1 is a zinc finger transcriptional repressor originally recognized for its role in T cell differentiation and lymphomas. Recent experiments reveal that gene-targeted Gfi-1-deficient mice are neutropenic and that Gfi-1 mutations cause human neutropenia. In both cases, myeloid progenitor cells los...

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Autors principals: Duan, Zhijun, Horwitz, Marshall
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC156304/
https://ncbi.nlm.nih.gov/pubmed/12721361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031694100
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