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Targets of the transcriptional repressor oncoprotein Gfi-1
Gfi-1 is a zinc finger transcriptional repressor originally recognized for its role in T cell differentiation and lymphomas. Recent experiments reveal that gene-targeted Gfi-1-deficient mice are neutropenic and that Gfi-1 mutations cause human neutropenia. In both cases, myeloid progenitor cells los...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156304/ https://ncbi.nlm.nih.gov/pubmed/12721361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031694100 |
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