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Sestrin Regulation of TORC1: Is Sestrin a Leucine Sensor?
Sestrins are highly conserved, stress-inducible proteins that inhibit target of rapamycin complex 1 (TORC1) signaling. Following their transcriptional induction, both vertebrate and invertebrate Sestrins turn on the AMP-activated protein kinase (AMPK) which activates the tuberous sclerosis complex (...
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| Vydáno v: | Sci Signal |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4902175/ https://ncbi.nlm.nih.gov/pubmed/27273098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf2885 |
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